Problem: Whether due to mergers and acquisitions, lab downsizing, upgrading or outsourcing, many pharmaceutical and biotech companies—large and small—are opting to sell R&D or manufacturing equipment no longer needed in their own labs. This presents a great opportunity for other institutions to obtain late-model, quality equipment at a reduced cost, direct from the working lab. While purchasing second-hand equipment can be a cost effective and socially acceptable way to go, there are potential pitfalls buyers should look out for including: unreliable sellers, equipment contamination, hidden fees, and unverified purchasing channels.