Articles by University of California - San Diego

Unusually high numbers of macrophages (in brown) were detected in cross-sections of lungs from COVID-19 patients using immunohistochemical techniques. Blue counterstain detects nuclei of all cells in the cross-section.

Fighting COVID-19 with a Cancer Drug

by University of California - San Diego

Molecule that helps cancer cells survive does the same thing for COVID-19 infections, allowing for repurposed treatments

Man with sleep apnea sleeping with a mask over his mouth

Diabetes Drug Shows Promise as a Therapy for a Sleep-Related Disorder

by University of California - San Diego

Advanced study of the drug tirzepatide finds it could be an effective treatment for obstructive sleep apnea

3d rendered image showing red and orange cancer cells on a blue tissue surface as if seen under enhanced scanning electron micrograph (SEM) showing the overall shape of the cells' surface at a very high magnification

Fighting Lung Cancer with Swimming Microscopic Robots

by University of California - San Diego

The bots deliver medication directly to metastatic tumors

a 3d illustration of a DNA molecule with one strand in blue and the other in red. Part of the red strand has been separated from the rest of the molecule. The strands are composed of many small lines connecting to dots with additional glowing dots surrounding the molecule, all on a dark blue background.

New Multiplexing Gene-Editing System Addresses Complex Diseases

by University of California - San Diego,Michelle Franklin

MOBEs are a new tool in disease modeling that install multiple point mutations at once

a 3d illustration of a human brain done in blue outline with many blue dots within it and some areas circled in red around the perimeter of the brain, on a black background with blue lines connecting dots like constellations

Researchers Discover Some Brain Cells Age Faster than Others

by University of California - San Diego

These cells are more prevalent in those afflicted with Alzheimer's disease

Lab Manager AI cancer drugs

Simulated Chemistry: New AI Platform Designs Tomorrow’s Cancer Drugs

by University of California - San Diego

The new platform helped UC San Diego scientists synthesize 32 potential multi-target cancer drugs

a photo of the microdisplay device showing the grid of LEDs lit up in two different colors, on a white surface

Flexible Microdisplay Monitors Brain Activity in Real-Time during Brain Surgery

by University of California - San Diego

The device represents a huge leap ahead to visualize brain activity to guide neurosurgeons

These images show microglia containing lipid droplets (white spots). Researchers at UC San Diego have revealed that in brains with Alzheimer’s and related diseases, neurons offload excess lipid droplets to microglia, which triggers further inflammation.

Innovative Microscopy Demystifies Metabolism of Alzheimer’s

by University of California - San Diego

State-of-the-art imaging techniques uncover metabolism driving Alzheimer’s disease, potential new treatment strategies

3d illustration of a DNA molecule with one strand in blue and the other in red. Part of the red strand has been separated from the rest of the molecule. The strands are composed of many small lines connecting to dots with additional glowing dots surrounding the molecule, all on a dark blue background.

New Genetic Analysis Tool Tracks Risks Tied to CRISPR Edits

by University of California - San Diego

System uses genetic fingerprints to identify unintentional ‘bystander’ edits linked with new disease therapies

a microfluidic device made of clear rectangular plastic with a white diamond in the center and visible flow channels being held in front of a black background

Detecting Pathogens Faster and More Accurately by Melting DNA

by University of California - San Diego

New analysis method can accurately detect pathogens in blood samples in less than half the time it takes for a culture