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Protein ‘Rescues’ Stuck Cellular Factories

by Johns Hopkins University School of Medicine

Using a powerful data-crunching technique, Johns Hopkins researchers have sorted out how a protein keeps defective genetic material from gumming up the cellular works. The protein, Dom34, appears to “rescue” protein-making factories called ribosomes when they get stuck obeying defective genetic instructions, the researchers report in the Feb. 27 issue of Cell.

Image showing cells after UV exposure, mostly pink with some green, where ribosomes activation is shown in pink and the DNA-initiated response is shown in green

UV Radiation Damage Leads to Ribosome Roadblocks, Causing Early Skin Cell Death

by Johns Hopkins Medicine

High-Speed Atomic Force Microscopy Visualizes Cell Protein Factories

by Kanazawa University

In a First for Cell Biology, Scientists Observe Ribosome Assembly in Real Time

by The Scripps Research Institute

The imaging feat clarifies how RNA molecules fold—and might one day translate into better medicines for a host of diseases

How Eating Less Can Slow the Aging Process

by Brigham Young University

Despite this study's observed connection between consuming fewer calories and improved lifespan, researcher assures that people shouldn't start counting calories and expect to stay forever young

Revving the Microbial Engine: Horsepower versus Fuel Efficiency in Bacterial Genomes

by University of Michigan

"To our knowledge, this is the first robust evidence linking the number of these ribosomal genes to bacterial growth rate and growth efficiency," researcher says

Looking Back 3.8 Billion Years into the Root of the “Tree of Life”

by Georgia Institute of Technology

Some of the keys to unlocking the origin of life lie encrypted in the ribosome, life’s oldest and most universal assembly of molecules

This Image Could Lead to Better Antibiotics

Berkeley Lab scientists create atomic-scale structure of ribosome attached to a molecule that controls its motion.