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Gene Therapy

Latin American technician working at the laboratory analyzing blood samples

Overcoming Batch-to-Batch Variation in Viral Vector Manufacturing

by Andy Tay, PhD

Process and product consistency is key to regulatory approval and therapeutic outcomes

3D CG rendered image of scientifically accurate Adeno-Associated Virus (AAV) Capsid Structure based on PDB : 1LP3 (ribbon style)

Optimizing Capsid Separation with Anion Exchange Chromatography

by Brandoch Cook, PhD

A Two-Step Process for Better Purification of Plasmids

A Two-Step Process for Better Purification of Plasmids

a photo representing hearing, showing a man's ear with his hand behind it, overlayed with a circular target and audiowaveforms

With Gene Editing, Mice with a Form of Inherited Deafness Can Hear Again

by National Center for Advancing Translational Sciences

Approach restores hearing in adult mice, opening new possibilities for treating genetic conditions in people

Improve AAV Product Recovery for Gene Therapy with Anion Exchange Polishing

Improve AAV Product Recovery for Gene Therapy with Anion Exchange Polishing

Avoid low full capsid yields with a novel, industry-verified polishing procedure

Effective AAV Processing Advances Gene Therapy Prospects

Effective AAV Processing Advances Gene Therapy Prospects

Recent improvements make AAV scale-up feasible for clinical applications

White moisture bubble helix on clear blue background with pure droplets

Gene Therapy Trial Shows Restored Hearing, Speech in Children Born Deaf

by Mass Eye and Ear

The therapy showed improvements over previous trial, such as sound source localization

an albino rat sits on a blue surface surrounded by various beakers and glassware filled with clear and blue liquids, with a black background

Gene Therapy Technique Successfully Relieves Pain, Repairs Damaged Spinal Discs in Mice

by Ohio State University

Nanocarriers loaded with DNA could one day replace opioids for pain relief

a 3d illustration of a DNA molecule with one strand in blue and the other in red. Part of the red strand has been separated from the rest of the molecule. The strands are composed of many small lines connecting to dots with additional glowing dots surrounding the molecule, all on a dark blue background.

Gene Linked to Epilepsy, Autism Decoded in New Study

by Northwestern University

Changes in SCN2A gene affect age of seizure onset, severity of other neurological impairments in affected children

Setting New Standards for Precision in Cell and Gene Therapy

ddPCR Resource Guide

by Bio-Rad Laboratories,Lab Manager

Setting New Standards for Precision in Cell and Gene Therapy

3D render of viruses

Trends and Advances in Digital PCR Viral Titer Quantification for CGT

by Bio-Rad Laboratories

Digital PCR (dPCR) goes beyond quantitative polymerase chain reaction (qPCR) and offers sensitive and accurate absolute quantification of viral infectivity

Illustration of scientists splicing DNA

The Cell and Gene Therapy Renaissance

by Sarah Kirsh, MSc

How cell and gene therapy, along with viral vectors, are shaping the future of medicine

Optimizing Cell and Gene Therapy Workflows

Optimizing Cell and Gene Therapy Workflows

Bioprocessing resource guide