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Gene Editing

Gene Editing

Trends in Genetics: A Tale of Two Decades

Clifford J. Steer, MD, discusses the changes that have taken place in genomics since the sequencing of the human genome in this Q&A with contributing editor Tanuja Koppal, PhD

Tomorrow’s Genome Editing

by Angelo DePalma, PhD

GMP-Ready Helper Plasmids for AAV Production

by AMSBIO

a photo representing hearing, showing a man's ear with his hand behind it, overlayed with a circular target and audiowaveforms

With Gene Editing, Mice with a Form of Inherited Deafness Can Hear Again

by National Center for Advancing Translational Sciences

Approach restores hearing in adult mice, opening new possibilities for treating genetic conditions in people

a 3d illustration of a DNA molecule with one strand in blue and the other in red. Part of the red strand has been separated from the rest of the molecule. The strands are composed of many small lines connecting to dots with additional glowing dots surrounding the molecule, all on a dark blue background.

RNA-Targeting Tech Manipulates Genes

by Donnelly Center, University of Toronto

The technology uses CRISPR to control RNA splicing

Altering Photosynthesis with CRISPR/Cas9

by University of Illinois at Urbana-Champaign

This is the first unbiased gene-editing approach to increase gene expression

Researchers Reveal the Molecular Mechanisms of Gene-Editing Tool

by School of Science University of Tokyo

Scientists shed light on the properties of "prime editor," a novel gene-editing tool

3d illustration of a DNA molecule with one strand in blue and the other in red. Part of the red strand has been separated from the rest of the molecule. The strands are composed of many small lines connecting to dots with additional glowing dots surrounding the molecule, all on a dark blue background.

New Genetic Analysis Tool Tracks Risks Tied to CRISPR Edits

by University of California - San Diego

System uses genetic fingerprints to identify unintentional ‘bystander’ edits linked with new disease therapies

vector illustration showing two strands of DNA on either side of the image with line art of various nucleotides in the middle, all done in shades of blue with teal and pink highlights

First-of-Its-Kind Super Minigene to Boost Spinal Muscular Atrophy Research

by Iowa State University

A shortened version of the gene that causes spinal muscular atrophy will make it easier to find potential treatments

The left half of the image is an electron microscopic image of nanoparticles seen as dark grey circles on a light grey background. The right half of the image shows the same nanoparticles as black dots attacking basal-like breast cancer cells shown in yellow with blue normal cells behind them.

GPS Nanoparticle Platform Precisely Delivers Therapeutic Payload to Cancer Cells

by Penn State

Equipped with novel homing abilities, the platform activates in cancer environments to release gene-editing tools

3D rendering of a human lymphocyte or t cell, a pink sphere covered with blue and purple protrusions, on a pink background

Gene Editing Precisely Repairs Immune Cells

by Max Delbrück Center for Molecular Medicine in the Helmholtz Association

New therapeutic strategy uses CRISPR-Cas9 to repair T cells that are defective due to rare disease of the immune system

a DNA double helix with one strand in red and one in blue, with a section of the red strand separated out, on a dark blue background

Highly Targeted CRISPR Delivery System Advances Gene Editing in Living Animals

by University of California - Berkeley

Antibody-targeted 'enveloped delivery vehicles' selectively edit T-cells to create CAR T-cells

Rows of tobacco plants growing in the sun

No Pollen, No Seeds

by North Carolina State University

Mitochondrial genome editing technique yields useful traits