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Drug Targets

This image shows the effect of protein-like polymers (red) in the brain cells of a mouse model. The nanoscale polymers are designed to alter the interaction between two proteins to combat oxidative stress in the cells.

Newly Developed Nanomaterial Mimics the Behavior of Proteins

by University of Wisconsin-Madison

Novel material could provide the basis for new neurodegenerative disease treatments

An icon of the human body has medication icons around it, and also 4 nodes. The nodes expand to say “Time of Day, Muscle Mass, Genetics, and Drug Toxicity,” and show icons. The words “Height and Weight” appear next to the human body.

A Closed-Loop Drug-Delivery System Could Improve Chemotherapy

by Massachusetts Institute of Technology

Newly developed inhibitor (green) prevents METTL16 (purple) from interaction with target RNA (turquois) and thus inhibits the transfer of the methyl group (Me).

A Promising Target for New RNA Therapeutics Now Accessible

by Max Planck Institute of Molecular Physiology

dark orange dots of bacteria in lines on petri dish held up by a hand in front of a window

A New Path to Drug Diversity

by Max Planck Institute for Terrestrial Microbiology

Research on protein evolution reveals new starting points for the rapid and targeted development of future drugs

a group of blue translucent marine invertebrates called tunicates or sea squirts clustered together on orange coral with a dark black background

How a Natural Compound from Sea Squirts Combats Cancer

by Institute for Basic Science

Scientists decipher how trabectedin outsmarts cancer cells’ DNA repair mechanism, paving the way for tailored treatments

Copper Transporter Potential New Treatment Target for Cardiovascular Disease

by Medical College of Georgia at Augusta University

Internal transporter also has the essential role of protecting the receptor that enables us to grow new blood vessels

Repurposed Drugs Present New Strategy for Treating COVID-19

by Korea Advanced Institute of Science and Technology

Virtual screening of 6,218 drugs and cell-based assays identifies best therapeutic medication candidates

A Promising New Drug Target for Autoimmune and Allergic Diseases

by Babraham Institute

Uncovering how 'dark matter' regions of the genome affect inflammatory diseases

Disease architecture of the sepsis cohort generated by the precisionlife platform

Mining of UK Biobank Finds 13 Human COVID-19 Risk Genes

by PrecisionLife

Study also identifies 59 compounds and drugs identified with potential for accelerated drug discovery

New Integrated Analytical Approach Reveals Molecules Involved in Disease

by Osaka University

Researchers establish a method that integrates genetic and molecular data to reveal tissue-specific features that have novel associations with diseases

Marker May Help Target Treatments for Crohn's Patients

by Cornell University

Researchers report that levels of a single molecule predict whether a patient has subtype 1 or subtype 2 of the disease

New Options for Breast Cancer Drug Development Found in Estrogen Receptors

by Case Western Reserve University

Case Western Reserve researchers uncover novel drug targets by piecing together receptor structures

IONTAS Signs Collaboration Agreement with LG Chem to Identify Therapeutic Oncology Leads

by IONTAS

IONTAS Limited announced it has signed a collaboration agreement with Korean-based LG Chem, Ltd.