DNA editing

A new CRISPR-free tool brings gene editing power to cells' second, smaller genome—the one in their mitochondria

A new type of DNA editing enzyme, developed in HHMI Investigator David Liu’s lab, lets scientists directly and permanently change single base pairs of DNA from A•T to G•C

This latest Reactions episode, explains how CRISPR works, how it is being used today, and what the future might bring for this landmark technology

Recent study shows that genomic sequence elements that were previously thought to be mere “junk DNA” have a critical role

Researchers at the University of Georgia have used a gene editing tool known as CRISPR/Cas to modify the genome of a tree species for the first time. Their research, published recently in the early online edition of the journal New Phytologist, opens the door to more rapid and reliable gene editing of plants.

Salk scientists use molecular "scissors" to eliminate mitochondrial mutations in eggs and embryos.

UCLA researchers devise new method to identify disease markers, a key step toward personalized medicine.

Scientists at The Scripps Research Institute (TSRI) have engineered a bacterium whose genetic material includes an added pair of DNA “letters,” or bases, not found in nature. The cells of this unique bacterium can replicate the unnatural DNA bases more or less normally, for as long as the molecular building blocks are supplied.  

Scientists at The Scripps Research Institute (TSRI) have found a way to apply a powerful new DNA-editing technology more broadly than ever before.