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INSIGHTS on Streamlining Clone Selection

Like great athletes and musicians, cells employed in cell-based assays or as expression systems for biopharmaceutical production are not born, but made. Cell lines that perform specifically and predictably arise from a population of cells that have undergone one or more genetic transformations (transfection) and are subsequently selected for desirable properties such as viability, protein or virus production; high culture density; or binding to drugs or antigens.

Ensuring Rapid and Efficient Cell Line Development

by Sartorius

The new thermal cycler on a white background

Bio-Rad Launches New Thermal Cyclers for Sequencing, Cloning, and Genotyping

by Bio-Rad Laboratories

The PTC Tempo Thermal Cycler on a white background

New Thermal Cyclers with Enhanced Usability to Support PCR Applications

by Bio-Rad Laboratories

The PTC Tempo 96 and PTC Tempo Deepwell thermal cyclers were designed to optimize PCR applications

Rice Breeding Breakthrough to Feed Billions

by University of California - Davis

New research could greatly lower the cost of hybrid rice seed, increasing its availability

BioRescue Produces Primordial Germ Cells from Northern White Rhino Stem Cells

by Leibniz Institute for Zoo and Wildlife Research

Researchers nourish the hope to prevent the extinction of the northern white rhino

Radiographs of Dolly's Skeleton Show No Signs of Abnormal Osteoarthritis

by University of Nottingham

Original concerns that cloning caused early-onset osteoarthritis in Dolly the sheep are unfounded

Cloning Thousands of Genes for Massive Protein Libraries

by Todd B. Bates-Rutgers University News Office

Scientists at Rutgers and other universities build technology that could lead to rapid discovery of new medicines and biomarkers hidden in genomes

Cow Gene Study Shows Why Most Clones Fail

by Lisa Howard-University of California Davis News Office

Gene expression pinpoints multiple anomalies likely to lead to pregnancy failure for clones

Researchers Create 'Naive' Pluripotent Human Embryonic Stem Cells

by Nicole Giese Rura-Whitehead Institute for Biomedical Research News Office

For years, researchers and patients have hoped that embryonic stem cells (ESCs)—capable of forming nearly any cell type in the body—could provide insight into numerous diseases perhaps even be used to treat them. Yet progress has been hampered by the inability to transfer research and tools from mouse ESC studies to their human counterparts, in part because human ESCs are “primed” and slightly less plastic than the mouse cells.

'Cloning' Could Make Structurally Pure Nanotubes for Nanoelectronics

by Other Author

Researchers from the University of Southern California (USC) and the National Institute of Standards and Technology (NIST) have demonstrated a technique for growing virtually pure samples of single-wall carbon nanotubes (SWCNTs) with identical structures, a process they liken to "cloning" the nanotubes.